Disable Capslock, Windows Key

[see AutoHotkey Tutorial]

Disable Caps Lock, Number Lock, Scroll Lock

; set the default state of the lock keys
SetCapsLockState, off
SetNumLockState, on
SetScrollLockState, off

; disable them
$NumLock::Return
$ScrollLock::Return
$CapsLock::Return

; make Caps Lock key do Control
CapsLock::Ctrl

[see AutoHotkey Key Syntax]

; make the capslock key behave as menu/AppsKey
CapsLock::AppsKey

The ▤ Menu key is actually very useful. See: Microsoft Keyboard Menu Key .

Disable Windows Logo Key

Disable Win Key Completely

;; disable the Win key completely
Lwin::return
Rwin::return

Disable Win Key Start Menu Behavior

;; disable Win key behavior of popping up the Start Menu, but don't disable Win+key combination
~LWin Up::Return
~RWin Up::Return

Disable Win+key Combination

;; disable some Win+key combination
#1::Return
#r::Return
#e::Return

Note: the ❖ Window+l (lock computer) cannot be disabled.

Disable F1 Help

#F1::Return

Instead of disable keys, it's better to set them to do something useful, such as switching app/window/tab, or copy cut paste.